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How does the apolipoprotein E genotype modulate the brain in aging and in Alzheimer’s disease? A review of neuroimaging studies

✍ Scribed by Maarit Lehtovirta; Mikko P Laakso; Giovanni B Frisoni; Hilkka Soininen

Book ID
117411053
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
74 KB
Volume
21
Category
Article
ISSN
0197-4580

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## Abstract ## Objective This study examined the association between a history of heavy alcohol use and smoking, presence of the apolipoprotein‐E epsilon 4 allele (__APOE__ ε4), and age of disease onset in a community dwelling sample of 685 Alzheimer's disease (AD) patients spanning three ethnic g