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How do small single-domain proteins fold?

โœ Scribed by Sophie E. Jackson


Book ID
114382698
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
174 KB
Volume
3
Category
Article
ISSN
1359-0278

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The thermal unfolding of three SH3 domains of the Tec family of tyrosine kinases was studied by differential scanning calorimetry and CD spectroscopy. The unfolding transition of the three protein domains in the acidic pH region can be described as a reversible two-state process. For all three SH3 d