How many class II immune response genes?
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Elizabeth Simpson; Rose Lieberman; Istvan AndΓ³; David H. Sachs; William E. Paul;
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Article
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1986
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Springer-Verlag
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English
β 654 KB
Ir genes mapping to the H-2 region of the mouse MHC reflect the natural function of class I and II molecules as restriction elements for antigen-specific T-cell responses (Simpson and Gordon 1977, Benacerraf and Germain 1978, Berzofsky 1980, in press, Schwartz 1984). Cytotoxic T cells are generally