How are TH1 and TH2 effector cells made?
β Scribed by Derk Amsen; Charalampos G Spilianakis; Richard A Flavell
- Book ID
- 108099629
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 559 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0952-7915
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Two types of T helper (Th) cells have been defined on the basis of their cytokine secretion patterns. The decision of a naive T cell to differentiate into Th1 or Th2 is crucial, since to a first approximation it determines whether a cell-mediated or humoral immune response is triggered against a par
## Abstract We characterized dendritic cells (DC) phenotypically and functionally between C57BL/6 (Th1βprone) and BALB/c (Th2βprone) mouse recipients in an in vivo sensitization model. Two strains of mice were presensitized with Lewis rat splenocytes as xenogeneic antigens. We found that BALB/c rec