## Key Points 1. The natural history of recurrent hepatitis C virus (HCV) is highly variable. Old donor age is a factor that has consistently been shown to affect disease progression. 2. Overall, immunosuppression determines the progression of HCV-related disease; however, the type of immunosuppre
β¦ LIBER β¦
Hot-topic debate on hepatitis C virus: The type of immunosuppression matters
β Scribed by James F. Trotter
- Book ID
- 102470667
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 79 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1527-6465
- DOI
- 10.1002/lt.22414
No coin nor oath required. For personal study only.
β¦ Synopsis
Key Points
- The treatment of rejection is an important factor associated with the severe recurrence of hepatitis C virus (HCV) after liver transplantation. 2. The effects of calcineurin inhibitors, corticosteroids, and mycophenolate mofetil on HCV recurrence are equivocal. 3. Cyclosporine is associated with a higher sustained virological response in patients treated for HCV. 4. Because insulin resistance and diabetes are associated with fibrosis in HCV-infected liver transplant recipients, the use of immunosuppressive agents without this side effect may slow the posttransplant disease progression. Liver Transpl 17:S20-S23, 2011. V C 2011 AASLD.
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