Serine palmitoyltransferase (SPT) catalyzes the first step in the sphingolipid biosynthetic pathway. Myriocin inhibits SPT and was shown to suppress the replication of hepatitis C virus (HCV) in vitro and in vivo. However, its effect on hepatitis B virus (HBV) replication is unknown. In this study,
Host sphingolipid biosynthesis as a target for hepatitis C virus therapy
β Scribed by Sakamoto, Hiroshi; Okamoto, Koichi; Aoki, Masahiro; Kato, Hideyuki; Katsume, Asao; Ohta, Atsunori; Tsukuda, Takuo; Shimma, Nobuo; Aoki, Yuko; Arisawa, Mikio
- Book ID
- 109914044
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 325 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1552-4450
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