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Host Indoleamine 2,3-Dioxygenase: Contribution to Systemic Acquired Tumor Tolerance

✍ Scribed by Johnson, Theodore S.; Munn, David H.


Book ID
115521654
Publisher
Informa plc
Year
2012
Tongue
English
Weight
601 KB
Volume
41
Category
Article
ISSN
0882-1039

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The priming of an appropriate anti-tumor T cell response rarely results in the rejection of established tumors. The characteristics of tumors that allow them to evade a T cell-mediated rejection are unknown for many tumors. We report on evidence that the expression of the immunosuppressive enzyme, i