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Host expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in normal colon tissue affects metastatic potential of colorectal cancer

✍ Scribed by Hideki Masuda; Hisayuki Aoki


Publisher
Springer
Year
1999
Tongue
English
Weight
633 KB
Volume
42
Category
Article
ISSN
0012-3706

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## Background: Matrix metalloproteinase-2 (mmp-2), which degrades the extracellular matrix or the basement membrane, has an essential role in tumor invasion and metastasis. to evaluate the roles of mmp-2, its inhibitor (tissue inhibitor of metalloproteinase-2 [timp-2]), and its activator (membrane-