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Hormone-related supplements and breast cancer risk: Need for improved measurement of supplement use

✍ Scribed by Beatrice A. Boucher; Lilian U. Thompson; Nancy Kreiger; Michelle Cotterchio

Publisher
John Wiley and Sons
Year
2008
Tongue
French
Weight
48 KB
Volume
123
Category
Article
ISSN
0020-7136

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✦ Synopsis

Alternative supplements such as herbal and other non-vitamin, non-mineral compounds may contain substantial amounts of bioactive ingredients, but despite widespread use, little is known about long-term risks or benefits. 1 Rebbeck et al. are to be congratulated for presenting data that address this gap, examining hormone-related supplements and breast cancer risk, for the first time. 2 We suggest, however, that aspects of their exposure measurement and results need to be reconsidered, to advance future risk assessment. We wish to primarily comment on three measurement limitations: the exclusion of supplements which are frequently used; the exclusion of supplements containing considerable amounts of hormone-related components; and the inclusion of items and decisions that

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