Hormone-receptor expression and activity of trastuzumab with chemotherapy in HER2-positive advanced breast cancer patients
✍ Scribed by Filippo Montemurro; Valentina Rossi; Maria Cossu Rocca; Rossella Martinello; Elena Verri; Stefania Redana; Laura Adamoli; Giorgio Valabrega; Anna Sapino; Massimo Aglietta; Giuseppe Viale; Aron Goldhirsch; Franco Nolè
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 223 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## BACKGROUND: Several large, randomized trials established the benefits of adjuvant trastuzumab with chemotherapy. However, the benefit for women with small, node‐negative HER2‐positive (HER2+) disease is unknown, as these patients were largely excluded from these trials. Therefore, a
## Abstract ## BACKGROUND: Only a portion of breast cancer patients currently selected for trastuzumab therapy respond. ## METHODS: Using a novel assay (HERmark) to quantify total human epidermal growth factor receptor 2 (HER2) expression, the authors examined outcomes in 102 trastuzumab‐treated