The effect of glucagon and insulin on the incorporation of l-I4C-acetate into cholesterol and fatty acids and on the enzymes involved in the first steps of cholesterol synthesis (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, 3hydroxy-3-methyl-glutaryl-coenzyme A synthase, and acetoacetyl-coenzym
Hormonal regulation of serum albumin production by pre- and postnatal rat hepatocytes in culture
β Scribed by I. N. Baranova; V. I. Gudoshnikov; V. P. Fedotov
- Publisher
- Springer US
- Year
- 1990
- Tongue
- English
- Weight
- 304 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0007-4888
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The effects of insulin, glucagon or Dexamethasone (DEX) and of glucagon with insulin or DEX were examined on the uptake of 2βamino [1β^14^C]isobutyric acid (AIB) and NβMethylβ2βamino [1β^14^C]isobutyric acid (NMe AIB) in monolayer cultures of rat hepatocytes. Insulin and glucagon stimul
Sustained production of plasma proteins, notably albumin, is a reliable indicator of the differentiated state ot hepatocytes. In this work, we have developed a fetal hepatocyte culture system where studying the regulation of albumin expression in proliferating liver cells. Our results show that unde
Hepatocyte DNA syntheGs, initiated by epidermal growth factor (EGF), is reversibly inhibited by 2% dimethyl sulfoxide (DMSO). At that concentration, both the survival of the cells in culture and the expression of differentiated functions are prolonged. DMSO does not affect thymidine uptake or EGF re
## Abstract The culture of fetal hepatocytes for 64 h in medium supplemented with 5 mM glucose, T3, insulin, and dexamethasone resulted in the coordinate precocious expression of malic enzyme mRNA, protein, and specific activity. T3 was the main inducer; meanwhile, insulin exerted a small synergist