Hormonal regulation of mouse mammary tumor growth
โ Scribed by M. Sluyser; B. Moncharmont; G. Ramp; C.C.J. de Goeij; S.G. Evers
- Book ID
- 116006285
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 1012 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-4731
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## Abstract The expression of the mouse mammary tumor virus (MMTV) in hormoneโinduced mammary tumors was investigated by means of a radioimmunoassay for two major MMTV proteins, gp52 and p27. MMTV proteins were isolated on lectin affinityโ and ionโexchange chromatography columns. The purified viral
## Abstract Explants of mouse mammary glands were cultured for one to five days in chemicallyโdefined medium containing various combinations of insulin, corticosterone, and prolactin. The changes in RNA content and synthesis effected by the several hormone combinations were assessed after one, two,