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Hormonal regulation of fatty acid metabolism in human hepatocytes in culture

✍ Scribed by Vonu, C.; Pégorier, J.P.; Koil, C.; Cirard, J.; Melcion, C.; Franco, D.

Book ID
122612569
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
47 KB
Volume
9
Category
Article
ISSN
0168-8278

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The effects of pancreatic hormones and cyclic AMP on long-chain fatty-acid metabolism were investigated in human hepatocytes isolated from 12 liver biopsy specimens and cultured for 4 days in an insulin-free medium. Glucagon (10(-6) mol/L) increased endogenous ketone body production by 150%. This re