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Hormonal regulation of fatty acid metabolism in cultured hepatocytes from rabbit fetuses

✍ Scribed by Prip-Buus, C; Pégorier, J.P.; Khol, C.; Girard, J.


Book ID
122087008
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
99 KB
Volume
9
Category
Article
ISSN
0261-5614

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The effects of pancreatic hormones and cyclic AMP on long-chain fatty-acid metabolism were investigated in human hepatocytes isolated from 12 liver biopsy specimens and cultured for 4 days in an insulin-free medium. Glucagon (10(-6) mol/L) increased endogenous ketone body production by 150%. This re