Hormonal activity of combinations of genistein, bisphenol A and 17β-estradiol in the female Wistar rat
✍ Scribed by Simone Schmidt; Gisela H. Degen; Jan Seibel; Torsten Hertrampf; Günter Vollmer; Patrick Diel
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 253 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0340-5761
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## Abstract Estrogenic compounds can activate protein kinase C (PKC), which is a calcium and phospholipid‐dependent serine/threonine kinase. In the present study, we investigated the role of 17β‐estradiol (E2), diethylstibestrol (DES), and bisphenol A (BPA) in the phosphorylation of substrate by PK
The present work describes time-dependent changes in the content of corticotropin-releasing hormone (CRH), adrenocorticotropin (ACTH), and P-endorphin (P-EP) in the hypothalamus (HT) and anterior pituitary (AP) and in the concentration of ACTH and P-EP in the plasma during the 17P estradiol (E,) ben