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Honokiol up-regulates prostacyclin synthease protein expression and inhibits endothelial cell apoptosis

✍ Scribed by Xiaoxue Zhang; Shizhong Chen; Yinye Wang


Book ID
113586523
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
427 KB
Volume
554
Category
Article
ISSN
0014-2999

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## Abstract Hyperglycemia is the hallmark of diabetes mellitus. Poor glycemic control is correlated with increased cardiovascular morbidity and mortality. High glucose can trigger endothelial cell apoptosis by de‐activation of endothelial nitric oxide synthase (eNOS). eNOS was recently demonstrated