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Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53

✍ Scribed by Saintigny, Yannick; Lopez, Bernard S

Book ID: 110066265
Publisher: Nature Publishing Group
Year: 2002
Tongue: English
Weight: 175 KB
Volume: 21
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1205040

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## Abstract As an oncoprotein, mutant p53 is a potential tumor‐specific target for cancer therapy. Most mutated forms of the protein are largely accumulated in cancer cells due to their increased stability. In the present study, we demonstrate that mutant p53 protein stability is regulated by gambo