## Abstract The phytochemical indole‐3‐carbinol (I3C), from cruciferous vegetables such as broccoli, has been shown to elicit a potent anti‐proliferative response in human breast cancer cell lines. Treatment of the immortalized human mammary epithelial cell line MCF10A with I3C induced a G1 cell cy
✦ LIBER ✦
Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint
✍ Scribed by Saintigny, Yannick; Rouillard, Danielle; Chaput, Brigitte; Soussi, Thierry; Lopez, Bernard S
- Book ID
- 110062339
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 321 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0950-9232
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2-Acetylaminofluorene (AAF) is a potent tumor promoter in rat liver carcinogenesis models. In the resistant hepatocyte model, AAF is combined with a growth stimulus for efficient promotion of preneoplastic lesions. The promoting property of AAF in this model is closely associated with mito-inhibitio