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Homocysteine Induces Phosphatidylserine Exposure in Cardiomyocytes through Inhibition of Rho Kinase and Flippase Activity

โœ Scribed by Sipkens, Jessica A.; Hahn, Nynke E.; van Nieuw-Amerongen, Geerten P.; Stehouwer, Coen D.A.; Rauwerda, Jan A.; van Hinsbergh, Victor W.M.; Niessen, Hans W.M.; Krijnen, Paul A.J.


Book ID
121700611
Publisher
S. Karger AG
Year
2011
Tongue
English
Weight
402 KB
Volume
28
Category
Article
ISSN
1015-8987

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PKC mediates cyclic stretch-induced card
โœ Jing Pan; Ugra S. Singh; Toshiyuki Takahashi; Yoshitomo Oka; Ants Palm-Leis; Bra ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 932 KB

## Abstract Signaling events, including Rho GTPases and protein kinase C (PKC), are involved in cardiac hypertrophy. However, the mechanisms by which these pathways cooperate during the hypertrophic process remain unclear. Using an in vitro cyclic stretch model with neonatal rat cardiomyocytes, we