Home-orienting behavior in rat pups: The effect of 2 and 3 generations of rehabilitation following intergenerational malnutrition

Initiation of focal hyperplastic hepatic

Initiation of focal hyperplastic hepatic lesions by transplacental administration of ethylnitrosourea in rats of F1 generation, and no transmission of the effect to F2 and F3 generations

✍ Katsuhiro Ogawa; Kinya Yokokawa; Takashi Tomoyori; Masanobu Narasaki 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 French ⚖ 359 KB

Administration of ethylnitrosourea (ENU) to pregnant rats in the late stage of gestation has been known to have a mainly neurocarcinogenic action on the progeny. However, when transplacental administration of ENU was combined in postnatal life with a brief dietary exposure to 2-acetylaminofluorene (