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hOGG1 Ser326Cys polymorphism is associated with risk of bladder cancer in a Chinese population: A case-control study

✍ Scribed by Lan Ma; Haiyan Chu; Meilin Wang; Danni Shi; Dongyan Zhong; Pu Li; Na Tong; Changjun Yin; Zhengdong Zhang


Book ID
114703265
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
221 KB
Volume
103
Category
Article
ISSN
1347-9032

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Ser326Cys polymorphism in the hOGG1 gene, which is involved in the repair of 8-hydroxyguanine in oxidatively damaged DNA, has been identified and the variant genotype appears to be related to susceptibility to certain cancers. We investigated the association between Ser326Cys polymorphism and squamo

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## Abstract The human oxoguanine glycosylase 1(hOGG1) gene encodes a DNA glycosylase that is involved in excision repair of 8‐OH‐dG (8‐hydroxy‐2‐deoxyguanine) from oxidatively‐damaged DNA. To determine whether hOGG1 plays a role in the risk for adenocarcinoma of the gallbladder, we tested the assoc