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hMLH1 and MGMT inactivation as a mechanism of tumorigenesis in monoclonal gammopathies

✍ Scribed by Martin, Paloma; Santón, Almudena; García-Cosio, Mónica; Bellas, Carmen


Book ID
109888414
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
463 KB
Volume
19
Category
Article
ISSN
0893-3952

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## Abstract ## BACKGROUND Silencing of tumor suppressor genes (TSG) by aberrant methylation (referred to as __methylation__) contributes to the pathogenesis of various human malignancies. However, little is known about the methylation of known and putative TSGs in monoclonal gammopathies. Thus, th