HLA genes and chronic hepatitis C severity
β Scribed by M. Asti; M. Martinetti; C. Zavaglia; M. Cuccia; S. Bruno; A. Cividini; G. Ideo; M.U. Mondelli; E. Silini
- Book ID
- 118568411
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 166 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0168-8278
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autoantibodies (anti-nuclear [ANA], 10 anti-smooth muscle To investigate the factors that may confer susceptibil- [SMA], 11 anti-GOR, 12 anti-liver, kidney microsomes [LKM] ity or protection to hepatitis C virus (HCV) infection and antibodies 13 ). Despite these observations, however, it reto HCV-a
Susceptibility to autoimmune hepatitis (AIH) is associated with the HLA A1-B8-DR3 haplotype, DR4 antigen, and, more specifically, the HLA DRB3\*0101, DRB1\*0301, and DRB1\*0401 alleles. Few investigators, however, have examined the HLA C locus in AIH, which warrants detailed study in view of its rec