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HLA antigens in familial Hodgkin's disease

✍ Scribed by Mark H. Greene; Elisabeth A. McKeen; Frederick P. Li; William A. Blattner; Joseph F. Fraumeni Jr.

Publisher: John Wiley and Sons
Year: 1979
Tongue: French
Weight: 352 KB
Volume: 23
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910230607

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✦ Synopsis

Abstract

In a study of 13 families prone to Hodgkin's disease, the probands showed significant excesses of the HLA antigens Bw35 (7 cases) and Bw37 (3 cases). Although based on a small number of patients, the results suggest that immunogenetic mechanisms account at least partly for the familial predisposition to Hodgkin's disease.

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