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HIV proteinase as a target for drug action

✍ Scribed by Margaret I. Johnston; H.S. Allaudeen; Nava Sarver

Book ID
119112333
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
415 KB
Volume
10
Category
Article
ISSN
0165-6147

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Current antiviral strategies against HIV rely on structure–function analysis of HIV reverse transcriptase (RT) and protease (PR). The third viral __pol__ gene product, HIV integrase (IN), is also a good target for drug discovery, since IN is essential for retroviral replication and, moreover, it has