✦ LIBER ✦

Potassium channels as targets for antiarrhythmic drug action

✍ Scribed by Dr. T. J. Colatsky; C. H. Follmer

Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 809 KB
Volume: 19
Category: Article
ISSN: 0272-4391
DOI: 10.1002/ddr.430190204

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Nuclear membrane receptors and channels:

Nuclear membrane receptors and channels: Potential therapeutical targets for drug action

✍ Ghassan Bkaily; Pedro D'Orléans-Juste; Pierre Pothier; Joao B. Calixto; Rosendo 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 676 KB

The recent use of confocal microscopy showed for the first time that the nucleus plays an important role in excitation-contraction and secretion coupling of several excitable and nonexcitable cells. It was also suggested that, like the sarcolemma membrane, the nuclear membrane indeed possesses chann

Stretch-activated channels in the heart:

Stretch-activated channels in the heart: Their role in arrhythmias and potential as antiarrhythmic drug targets

✍ David A. Saint 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 81 KB

DNA as a target for drug action

✍ F. Gago 📂 Article 📅 1989 🏛 Elsevier Science 🌐 English ⚖ 132 KB

Potassium ion channels and human disease

Potassium ion channels and human disease: phenotypes to drug targets?

✍ Mark E Curran 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 987 KB

A significant difficulty faced by the pharmaceutical industry is the initial identification and selection of macromolecular targets upon which de novo drug discovery programs can be initiated. A drug target should have several characteristics: known biological function; robust assay systems for in v

The lymphocyte potassium channels Kv1.3

The lymphocyte potassium channels Kv1.3 and KCa3.1 as targets for immunosuppression

✍ Jenny Lam; Heike Wulff 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB

## Abstract The voltage‐gated Kv1.3 and the calcium‐activated KCa3.1 potassium channel modulate many calcium‐dependent cellular processes in immune cells, including T‐cell activation and proliferation and have therefore been proposed as novel therapeutic targets for immunomodulation. Kv1.3 is highl

Novel Therapeutic Targets for Antiarrhyt

Novel Therapeutic Targets for Antiarrhythmic Drugs. Edited by George E. Billman.

✍ Ahmed S. Mehanna 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 124 KB