HIV-1 reverse transcriptase connection subdomain mutations involved in resistance to approved non-nucleoside inhibitors
✍ Scribed by Luis Menéndez-Arias; Gilberto Betancor; Tania Matamoros
- Book ID
- 113458740
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 684 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0166-3542
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📜 SIMILAR VOLUMES
## Abstract An extended spectrum of HIV‐1 reverse‐transcriptase (RT) mutations in HAART‐treated patients has been recently described. To verify the possible association of previously unreported RT mutations with a decrease of phenotypic susceptibility to nucleoside (NRTIs) and non‐nucleoside (NNRTI
## Abstract Recent studies have highlighted the need of investigating the in vivo role of ribonuclease H (RNase H) in nucleoside reverse transcriptase inhibitors (NRTIs) resistance. The prevalence of RNase H mutations in naive and in NRTI pre‐treated patients in regimen failure were compared and so