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HIV-1: Gambling on the evolution of drug resistance?

✍ Scribed by Leigh Brown, Andrew J.; Richman, Douglas D.


Book ID
109927688
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
667 KB
Volume
3
Category
Article
ISSN
1078-8956

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We studied the relationship between recombination and the fixation time of multiple drug resistance mutations after HIV-1 drug therapy, under a set of different realistic scenarios. We have generalized a previous model by Bretscher et al. [Bretscher, Althaus, Muller, Bonhoeffer, 2004. Recombination