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Transmitted drug-resistant HIV-1 in primary HIV-1 infection; incidence, evolution and impact on response to antiretroviral therapy

✍ Scribed by J Fox; S Dustan; M McClure; J Weber; S Fidler


Book ID
111063332
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
292 KB
Volume
7
Category
Article
ISSN
1464-2662

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Baseline genotype resistance analysis was carried out in 48 adults with primary HIV-1 infection between 1995 and 1998 before starting early combination therapy. Seventeen percent (8/48) of the isolates displayed key mutations conferring resistance to reverse transcriptase (RT) inhibitors such as ami