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Histopathological features of breast tumours inBRCA1,BRCA2and mutation-negative breast cancer families

✍ Scribed by Hannaleena Eerola, Päivi Heikkilä, Anitta Tamminen…


Book ID
120700460
Publisher
BioMed Central
Year
2004
Tongue
English
Weight
151 KB
Volume
7
Category
Article
ISSN
1465-5411

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We have screened index cases from 25 Russian breast/ovarian cancer families for germ-line mutations in all coding exons of the BRCA1 and BRCA2 genes, using multiplex heteroduplex analysis. In addition we tested 22 patients with breast cancer diagnosed before age 40 without family history and 6 patie