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Basal cytokeratins in breast tumours amongBRCA1,BRCA2and mutation-negative breast cancer families

✍ Scribed by Hannaleena Eerola, Mira Heinonen, Päivi Heikkilä, Outi Kilpivaara…


Book ID
120699254
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
142 KB
Volume
10
Category
Article
ISSN
1465-5411

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We have screened index cases from 25 Russian breast/ovarian cancer families for germ-line mutations in all coding exons of the BRCA1 and BRCA2 genes, using multiplex heteroduplex analysis. In addition we tested 22 patients with breast cancer diagnosed before age 40 without family history and 6 patie