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Histones and lung cancer: are the histone deacetylases a promising therapeutic target?

✍ Scribed by Petta, Vasiliki; Gkiozos, Ioannis; Strimpakos, Alex; Syrigos, Konstantinos

Book ID
121611382
Publisher
Springer
Year
2013
Tongue
English
Weight
416 KB
Volume
72
Category
Article
ISSN
0344-5704

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## Abstract Histone deacetylases (HDACs) are involved in chromatin remodeling and modification of nonhistone transcription regulatory proteins, thus modulating the expression of genes important for complex biological events. Dysregulation of HDACs and aberrant chromatin acetylation and deacetylatio