✦ LIBER ✦

Histone variants in mouse centromeric chromatin

✍ Scribed by Valya Russanova; Elena Stephanova; Iliya Pashev; Roumen Tsanev

Book ID: 104671587
Publisher: Springer
Year: 1989
Tongue: English
Weight: 933 KB
Volume: 90
Category: Article
ISSN: 0300-8177
DOI: 10.1007/bf00225215

No coin nor oath required. For personal study only.

✦ Synopsis

Highly purified centromeric heterochromatin was isolated from mouse liver nuclei and the pattern of core histone variants was analyzed. In comparison with total chromatin, the centromeric heterochromatin of young animals was characterized by (1) enrichment in the replication-dependent variants H2A1, H2B2 and H3(2), (2) reduced amount of the minor variant H2Az and (3) absence of ubiquitinated molecules of H2A. This specific variant pattern changed upon ageing as a result of accumulation of replacement variants so that in adult animals both chromatin preparations exhibited similar pattern for H2A and H2B, while the difference in the profile of H3 variants was preserved.

📜 SIMILAR VOLUMES

The cenH3 histone variant defines centro

The cenH3 histone variant defines centromeres inGiardia intestinalis

✍ S. C. Dawson; M. S. Sagolla; W. Z. Cande 📂 Article 📅 2006 🏛 Springer 🌐 English ⚖ 669 KB

Histone variants: making structurally an

Histone variants: making structurally and functionally divergent nucleosomes and linkers in chromatin

✍ Leilei Shi; Yuda Fang 📂 Article 📅 2011 🏛 SP Higher Education Press 🌐 English ⚖ 190 KB

Loading time of the centromeric histone

Loading time of the centromeric histone H3 variant differs between plants and animals

✍ Inna Lermontova; Jörg Fuchs; Veit Schubert; Ingo Schubert 📂 Article 📅 2007 🏛 Springer 🌐 English ⚖ 199 KB

Histones and chromatin structure in hype

Histones and chromatin structure in hyperthermophilic Archaea

✍ Rowan A. Grayling; Kathleen Sandman; John N. Reeve 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 782 KB

Histone acetylation in chromatin structu

Histone acetylation in chromatin structure and transcription

✍ Grunstein, Michael 📂 Article 📅 1997 🏛 Nature Publishing Group 🌐 English ⚖ 262 KB

Histone acetylation in chromatin structu

Histone acetylation in chromatin structure and transcription

✍ Grunstein, Michael 📂 Article 📅 1997 🏛 Nature Publishing Group 🌐 English ⚖ 262 KB

'The amino termini of histones extend from the nucleosomal core and are modified by acetyltransferases and deacetylases during the cell cycle. These acetylation patterns may direct histone assembly and help regulate the unfolding and activity of genes.