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Histone methyltransferase gene SETD2, a novel tumor suppressor gene in clear cell renal cell carcinoma

✍ Scribed by Gerben Duns; Inge van Duivenbode; Jan Osinga; Harrie Hollema; Eva van den Berg-De Ruiter; Robert M.W. Hofstra; Klaas Kok


Book ID
113513804
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
40 KB
Volume
203
Category
Article
ISSN
0165-4608

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## Abstract Renal clear cell carcinoma (RCCC) is a malignant tumor with poor prognosis caused by the high incidence of metastasis to distal organs. Although metastatic RCCC cells frequently show aberrant cytoskeletal organization, the underlying mechanism has not been elucidated. DAL‐1/4.1B is an a