## Abstract Cell cycle progression beyond the G~1~/S phase transition requires the activation of a transcription complex containing histone nuclear factor P (HiNFβP) and nuclear protein mapped to ataxia telangiectasia (p220^NPAT^) in response to cyclin dependent kinase 2 (CDK2)/cyclin E signaling.
Histone H4, the cell cycle and A question of integrity
β Scribed by Bryan M. Turner
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 393 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0265-9247
No coin nor oath required. For personal study only.
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## Abstract Cell cycle progression into S phase requires the induction of histone gene expression to package newly synthesized DNA as chromatin. Cyclin E stimulation of CDK2 at the Restriction point late in G1 controls both histone gene expression by the p220^NPAT^/HiNFβP pathway and initiation of
## Abstract The CCAAT displacement protein (CDPβcut/CUTL1/cux) performs a key proliferationβrelated function as the DNA binding subunit of the cell cycle controlled HiNFβD complex. HiNFβD interacts with all five classes (H1, H2A, H2B, H3, and H4) of the cellβcycle dependent histone genes, which are