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Histone deacetylase inhibitors induce mitotic slippage

✍ Scribed by Stevens, F E; Beamish, H; Warrener, R; Gabrielli, B


Book ID
110072767
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
573 KB
Volume
27
Category
Article
ISSN
0950-9232

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## Abstract Histone deacetylase (HDAC), inhibitors represent a new class of targeted anti‐cancer agents. Several of these compounds are in clinical trials with significant activity against a spectrum of both hematologic and solid tumors at doses that are well tolerated by the patients. The HDAC inh