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Histone Deacetylase Inhibitors from Burkholderia thailandensis

✍ Scribed by Klausmeyer, Paul; Shipley, Suzanne M.; Zuck, Karina M.; McCloud, Thomas G.

Book ID: 115463842
Publisher: American Chemical Society
Year: 2011
Tongue: English
Weight: 933 KB
Volume: 74
Category: Article
ISSN: 0163-3864
DOI: 10.1021/np200532d

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## Abstract Histone deacetylase (HDAC), inhibitors represent a new class of targeted anti‐cancer agents. Several of these compounds are in clinical trials with significant activity against a spectrum of both hematologic and solid tumors at doses that are well tolerated by the patients. The HDAC inh