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Histone deacetylase inhibitors: Anticancer compounds

✍ Scribed by Karen T. Smith; Jerry L. Workman

Book ID: 116307682
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 181 KB
Volume: 41
Category: Article
ISSN: 1357-2725
DOI: 10.1016/j.biocel.2008.09.008

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## Abstract Cancer is as much an epigenetic disease as it is a genetic and cytogenetic disease. The discovery that drastic changes in DNA methylation and histone modifications are commonly found in human tumors has inspired various laboratories and pharmaceutical companies to develop and study epig