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Histone deacetylase inhibitors: A new mode for inhibition of cholesterol metabolism

โœ Scribed by Sridar V Chittur; Niquiche Sangster-Guity; Paulette J McCormick


Book ID
115004794
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
761 KB
Volume
9
Category
Article
ISSN
1471-2164

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Histone deacetylase inhibitors: Understa
โœ Ana Villar-Garea; Manel Esteller ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 346 KB

## Abstract Cancer is as much an epigenetic disease as it is a genetic and cytogenetic disease. The discovery that drastic changes in DNA methylation and histone modifications are commonly found in human tumors has inspired various laboratories and pharmaceutical companies to develop and study epig