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Histone acetyltransferase activity of p300 enhances the activation of IL-12 p40 promoter

✍ Scribed by Haijing Sun; Jun Lu; Liang Wei; Xiuli Wang; Xin Xu; Mei Dong; Baiqu Huang

Book ID
116755380
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
160 KB
Volume
41
Category
Article
ISSN
0161-5890

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## Abstract Interleukin‐18 (IL‐18), an important regulator of innate and acquired immune responses expressed from a variety of cell types, is a pleiotropic cytokine in the development of T helper type 1 (Thl) cells. The p300/CBP (CREB‐binding protein) coactivator proteins are important histone acet