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E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300

✍ Scribed by Brandy D. Hyndman; Patrick Thompson; Richard Bayly; Graham P. Côté; David P. LeBrun

Book ID
116272731
Publisher
Elsevier
Year
2012
Tongue
English
Weight
767 KB
Volume
1819
Category
Article
ISSN
1874-9399

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## Abstract Interleukin‐18 (IL‐18), an important regulator of innate and acquired immune responses expressed from a variety of cell types, is a pleiotropic cytokine in the development of T helper type 1 (Thl) cells. The p300/CBP (CREB‐binding protein) coactivator proteins are important histone acet