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Histochemical staining of the acetylcholine receptor, acetylcholinesterase, and the axon terminal

✍ Scribed by Ms. Elizabeth K. Bjornskov; Dr. Forbes H. Norris Jr.; Dr. Janis Mower-Kuby

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
475 KB
Volume
5
Category
Article
ISSN
0148-639X

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✦ Synopsis

Abstract

Fluoresceinated alpha‐bungarotoxin (α‐BT) and the Pestronk‐Drachman neuromuscular stain were combined to demonstrate the acetylcholine receptor, the junctional acetylcholinesterase, and the nerve terminal on the same endplate. The method is reliable and rapid. Synapses in both normal muscle and muscle affected by amyotrophic lateral sclerosis (ALS) are equally well displayed.

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Histochemistry of acetylcholine receptor
Histochemistry of acetylcholine receptors and acetylcholinesterase during the formation of neuromuscular junctions in the urodele Hynobius nigrescens
✍ Masahiro Tabuchi; Keiko Fujikura; Sakae Inoue πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 653 KB

The development and structure of neuromuscular junctions (n-m-js) in stylopodia of forelimbs of larvae and adults of Hynobius nigrescens were histochemically investigated for acetylcholine receptors (AChRs) and acetylcholinesterase (AChE) activity. In larvae, the tetramethyl rhodamine-labelled Ξ±-bun