Histochemical investigation of adjuvant-induced arthritis
β Scribed by Fred R. Nusbickel; Henry Troyer
- Book ID
- 102749926
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 698 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0004-3591
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β¦ Synopsis
Abstract
Rats with adjuvantβinduced arthritis were observed to have increased alkaline phosphatase, acid phosphatase (two isozymes), and ATPase activity in the radial zone of articular cartilage, at the osteochondral junction, and in the bone marrow elements. A qualitative and quantitative reduction of azure A, PAS, colloidal iron, alcian blue critical electrolyte concentration staining (0.4 and 0.9 M (mg Cl~2~) was also observed in corresponding areas. These findings suggest the degradation of the articular cartilage matrix with possible simultaneous or resultant calcification.
π SIMILAR VOLUMES
Objective. To define the effects of incomplete Freund's adjuvant (LCFA) on subsequent arthritis induced by complete Freund's adjuvant (CFA) and type I1 collagen (CII) in DA and Lewis rats. Methods. ICFA was injected into DA and Lewis rats before CFA or CII injection. Results. DA rats previously in