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Histamine /HA/ uptake and release by endothelial cells in primary cultures of embryonic brain of rats

✍ Scribed by Huszti, Z.; Joó, F.; Deli, M.


Book ID
122956872
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
140 KB
Volume
21
Category
Article
ISSN
0197-0186

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Labelled histamine was taken up into cultured glial cells of chick embryonic brain by a system with high affinity for histamine and diffusion. The active uptake, occurring at low concentrations of the amine, was Na+ dependent and gave an apparent K, of 0.24 pM and a V, , , of 0.31 pmol x mg protein