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Histamine elevates the expression of Ets-1, a protooncogen in human melanoma cell lines through H2 receptor

✍ Scribed by Hargita Hegyesi; Barnabás Horváth; Éva Pállinger; Zoltán Pós; Viktor Molnár; András Falus

Book ID
116465510
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
188 KB
Volume
579
Category
Article
ISSN
0014-5793

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## Abstract ## Background. The protooncogenes Ets‐1 and Ets‐2 are involved in carcinogenesis of different tumors. Nimesulide, a selective cyclooxygenase‐2 (COX‐2) inhibitor, has antiproliferative effects on tumor cells. The question arises whether nimesulide influences Ets‐1 and Ets‐2 synthesis in