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Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories

✍ Scribed by Heldt, S A; Stanek, L; Chhatwal, J P; Ressler, K J


Book ID
110060234
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
281 KB
Volume
12
Category
Article
ISSN
1359-4184

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## Abstract Using two different mRNA synthesis inhibitors, we show that blockade of hippocampal gene expression during restricted posttraining or postretrieval time windows hinders retention of long‐term spatial memory for the Morris water maze task, without affecting short‐term memory, nonspatial