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Hippocampal synaptic plasticity and spatial learning are impaired in a rat model of sleep fragmentation

✍ Scribed by Jaime L. Tartar; Christopher P. Ward; James T. McKenna; Mahesh Thakkar; Elda Arrigoni; Robert W. McCarley; Ritchie E. Brown; Robert E. Strecker

Book ID: 109024451
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 444 KB
Volume: 23
Category: Article
ISSN: 0953-816X
DOI: 10.1111/j.1460-9568.2006.04808.x

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## Abstract Schizophrenia is mostly a progressive psychiatric illness. Although cognitive changes in chronic schizophrenia have been investigated, little is known about the consequences of a single psychotic episode on memory mechanisms and formation. We investigated changes in hippocampal long‐ter