𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hinokitiol activates the hypoxia-inducible factor (HIF) pathway through inhibition of HIF hydroxylases

✍ Scribed by Myong Jin Lee; Jeong Won Kim; Eun Gyeong Yang

Book ID
116300227
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
326 KB
Volume
396
Category
Article
ISSN
0006-291X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Regulation of HIF prolyl hydroxylases by
Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors
✍ Olga Aprelikova; Gadisetti V.R. Chandramouli; Matthew Wood; James R. Vasselli; J πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 322 KB

## Abstract Hypoxia and induction of hypoxia‐inducible factors (HIF‐1Ξ± and HIF‐2Ξ±) is a hallmark of many tumors. Under normal oxygen tension HIF‐alpha subunits are rapidly degraded through prolyl hydroxylase dependent interaction with the von Hippel‐Lindau (VHL) tumor suppressor protein, a componen