HILIC and mixed-mode chromatography: The rising stars in separation science
✍ Scribed by Michael Lämmerhofer
- Book ID
- 102444571
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 281 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1615-9306
No coin nor oath required. For personal study only.
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## Abstract The analysis of highly hydrophilic, ionic, and polar compounds has been performed by HILIC‐ESI‐MS for the last few years. The use of low aqueous/high polar organic solvent content in HILIC separation mobile phase is almost ideal for ESI‐MS detection in many cases, resulting in increased
## Abstract Phosphorylated carbohydrates are important intracellular metabolites and thus of prime interest in metabolomics research. Complications in their analysis arise from the existence of structural isomers that do have similar fragmentation patterns in MS/MS and are hard to resolve chromatog
Hydrophobic anion exchangers were formed by cobonding both ionic and hydrophobic ligands to silica gel. These phases were used to separate single-stranded oligonucleotides and double-stranded DNA restriction fragments. By varying the ratio of n-octyldimethylsilane and either 3-chloropropyldimethylsi
## Abstract The multi‐criteria decision making (MCDM) method was applied for the optimization of the separation of eight coumarin compounds in mixed micellar liquid chromatography (MLC). In order to achieve this goal the usefulness of Derringer's desirability function for the evaluation of the two