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Highly-substituted pyrazoles and pyridazines by MIRC reactions of hydrazone anions and nitrobutadienic fragments

✍ Scribed by Bianchi, Lara; Carloni-Garaventa, Alessandro; Maccagno, Massimo; Petrillo, Giovanni; Scapolla, Carlo; Tavani, Cinzia


Book ID
121958642
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
1000 KB
Volume
53
Category
Article
ISSN
0040-4039

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## Abstract 5‐(2‐Aminophenyl)isoxazoles are obtained in good yields by the reaction of 2‐(trifluoromethyl)aniline with dilithio derivatives of oximes of acetone, 3‐pentanone, propiophenone, and cyclohexanone. An analogous synthesis of a substituted isoxazole from 4‐(trifluoromethyl)aniline and 3‐pe